CJC-1295 vs BPC-157 Dosage: Two Different Records

CJC-1295 vs BPC-157 dosage: per-kilogram trial doses for one, no reviewed figure for the other, how often each is cited, and units per vial at each strength.

Medibact Guides · Published 2026-11-02

Illustration: A clear glass vial with pale blue liquid on a white lab bench, softly lit.
Illustration

CJC-1295 and BPC-157 turn up in the same online stacks and the same search, but they share almost nothing except a vial size. One is an engineered version of a hormone that was taken through two dose-ranging studies and a phase 2 trial before its developer stopped; the other is a peptide whose human record is three small reports and whose dose figures were never measured against anything. This page puts the two records next to each other — what each source states, how often each figure is cited, and what the figures look like on a syringe (sources opened 2026-11-02). It reports figures; it suggests none.

The full record for each is on its own page: CJC-1295 dosage and BPC-157 dosage. Vial arithmetic for any water volume is in the CJC-1295 calculator and the BPC-157 calculator.

The two records in one table

CJC-1295 (with DAC) BPC-157
What it is 29-residue GHRH analogue with an albumin-binding Drug Affinity Complex Synthetic 15-residue peptide, "body protection compound"
Molecular weight (PubChem) 3,647.2 g/mol 1,419.5 g/mol
How it acts GHRH receptor on the pituitary; raises growth hormone and IGF-1 No receptor established in the sources read
Human dosing source Two 2006 studies, 30 to 90 mcg/kg SC, single or weekly/biweekly None; three uncontrolled reports, 30 people
Half-life 5.8 to 8.1 days; about 8 days Under 30 minutes in rats and dogs
ClinicalTrials.gov, 2026-11-02 1 study, terminated 4 studies, 1 completed (a gummy)
Circulating figure (this site, 2026-09-18) 1 to 2 mg a week 250 to 500 mcg once or twice daily
US label (DailyMed, 2026-11-02) None None

The row that decides how to read everything else is the dosing source. CJC-1295's figure comes from studies built to find a dose and measure what it did to growth hormone; BPC-157's comes from convention.

What the CJC-1295 studies did

Teichman and colleagues ran two randomised, placebo-controlled, double-blind ascending-dose trials in healthy adults aged 21 to 61, lasting 28 and 49 days. The first gave one of four single subcutaneous doses; the second gave two or three doses weekly or every two weeks. A single injection raised mean growth hormone two- to tenfold for six days or more and IGF-1 one-and-a-half- to threefold for nine to eleven days; after repeated doses IGF-1 stayed above baseline for up to 28 days. The authors judged it relatively well tolerated, particularly at 30 or 60 mcg/kg, and reported no serious adverse reactions.

Ionescu and Frohman gave healthy men aged 20 to 40 a single 60 or 90 mcg/kg injection and sampled blood every 20 minutes overnight before and a week after. Growth hormone kept its pulses; what rose was the trough between them, 7.5-fold, lifting mean growth hormone by 46% and IGF-1 by 45%. The two doses did not differ.

The developer, ConjuChem, then registered a 12-week phase 2 trial in people with HIV-associated abdominal fat (NCT00267527, enrolment listed as 120). It is marked terminated and has no posted results. No later registration exists.

What the BPC-157 record holds

The 2026 systematic review by Poolton and colleagues, searched to 1 June 2026, found three human studies: knee injections in 16 people, bladder instillation in 12 and an intravenous safety pilot in 2. All were uncontrolled and judged poor quality. The registry adds a completed 40-person study of a 500 mcg gummy with no control arm, a recruiting hamstring-strain study and a rotator-cuff study not yet recruiting. The pharmacokinetics are known only from rats and dogs, set out on BPC-157 half-life. The daily figures in circulation trace to none of these.

Weekly against daily

The schedules attached to each compound follow from how long it lasts. CJC-1295 with DAC attaches to albumin in the blood and carries a half-life of about a week, which is why its studies gave single injections and weekly or biweekly repeats. BPC-157 disappears within minutes in animal plasma, and the figures cited for it are daily. Put on one calendar, a weekly 2 mg of CJC-1295 and a twice-daily 500 mcg of BPC-157 amount to 2 mg and 7 mg a week: the compound with the smaller per-injection figure is cited at the larger weekly total. That comparison is arithmetic on circulating figures, not a finding about either.

The no-DAC form is a separate case. It is a different molecule in practice, cleared in minutes, and is cited at 100 to 300 mcg one to three times a day on vendor pages; no human study of it was found. The DAC and no-DAC distinction is set out on CJC-1295 DAC vs no DAC.

The arithmetic per vial

Both are sold in 5 mg and 10 mg vials, and units depend only on concentration.

Vial Water Concentration mcg per U-100 unit 250 mcg 500 mcg 1 mg 2 mg
5 mg 1 mL 5,000 mcg/mL 50 5 units 10 20 40
5 mg 2 mL 2,500 mcg/mL 25 10 20 40 80
5 mg 3 mL 1,667 mcg/mL 16.7 15 30 60 120
10 mg 1 mL 10,000 mcg/mL 100 2.5 5 10 20
10 mg 2 mL 5,000 mcg/mL 50 5 10 20 40
10 mg 3 mL 3,333 mcg/mL 33.3 7.5 15 30 60

The 250 and 500 mcg columns are where BPC-157's circulating figures land, the 1 and 2 mg columns where CJC-1295's do. A 5 mg vial holds two and a half 2 mg amounts or ten 500 mcg amounts. The trial doses of CJC-1295, 2.1 to 6.3 mg at 70 kg, would need between 42% and more than a whole 5 mg vial per injection. One unit is 0.01 mL; the insulin syringe units page shows the barrels, and the water volumes for each compound are worked on CJC-1295 reconstitution and BPC-157 reconstitution.

What is not established

No study has compared the two or given them together. The CJC-1295 trials were short studies in healthy adults measuring hormone levels, not outcomes, and the one patient trial stopped without results. BPC-157 has no controlled human study at all. Medibact's CJC-1295 guide and BPC-157 guide cover the compounds. Decisions about administering anything belong with a clinician.

Sources and dates

Opened 2026-11-02: PubMed abstracts for Teichman SL et al., J Clin Endocrinol Metab 2006;91(3):799-805 (PMID 16352683) and Ionescu M, Frohman LA, J Clin Endocrinol Metab 2006;91(12):4792-7 (PMID 17018654); ClinicalTrials.gov record NCT00267527 and searches "CJC-1295" (1) and "BPC-157" (4); DailyMed SPL searches for both (0); PubChem CIDs 91971820 and 9941957. Carried with their read dates: circulating figures from this site's CJC-1295 and BPC-157 dosage pages (2026-09-18); the Poolton 2026 systematic review (2026-10-22); the BPC-157 rat and dog half-lives (this site's half-life page, 2026-10-28). Molecule-count, weekly-total and unit arithmetic by this site. Corrections go to the contact page.

Frequently asked questions

What is the difference between CJC-1295 and BPC-157?

CJC-1295 is a modified growth-hormone-releasing hormone that signals the pituitary to release growth hormone; the DAC form lasts about a week. BPC-157 is a synthetic 15-residue peptide with a large animal literature on tissue repair and no established receptor. One has two small dose-ranging studies in healthy adults; the other has three uncontrolled human reports.

What CJC-1295 dose was used in human studies?

Single subcutaneous doses of 30 to 90 mcg/kg of the DAC form, and in one study two or three weekly or biweekly doses. At 70 kg that is 2.1 to 6.3 mg per injection. The 1 to 2 mg weekly figure on vendor pages is lower than any trial dose.

How many units is 2 mg of CJC-1295 compared with 500 mcg of BPC-157?

From a 5 mg vial in 2 mL (2,500 mcg/mL), 2 mg is 80 units and 500 mcg is 20 units on a U-100 syringe. From a 10 mg vial in 2 mL (5,000 mcg/mL) they are 40 and 10 units. The concentration, not the compound, sets the units.

Are CJC-1295 and BPC-157 used together?

Some clinic and vendor pages list them together. No registered study has given the two together and none has measured whether one changes the other. They are cited on different schedules: CJC-1295 with DAC weekly, BPC-157 daily.

Is CJC-1295 no DAC the same as CJC-1295 in the trials?

No. Every human study used the DAC form, which binds albumin and lasts days. The no-DAC form sold as 'CJC-1295 no DAC' is the same peptide as Mod GRF 1-29, cleared in minutes, and no human study of it was found. Its 100 to 300 mcg figures come from vendor pages only.